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Prenatal treprostinil reduces the pulmonary hypertension phenotype in the rat model of congenital diaphragmatic hernia

BACKGROUND: Persistent pulmonary hypertension (PH) causes significant mortality and morbidity in infants with congenital diaphragmatic hernia (CDH). Since pulmonary vascular abnormalities in CDH develop early during foetal development, we hypothesized that prenatal maternal administration of trepros...

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Detalles Bibliográficos
Autores principales: De Bie, Felix Rafael, Halline, Christopher Gates, Kotzur, Travis, Hayes, Kevin, Rouse, Christopher Copeland, Chang, Jonathan, Larson, Abby Christine, Khan, Sameer Ahmad, Spina, Ashley, Tilden, Samantha, Russo, Francesca Maria, Hedrick, Holly Lee, Deprest, Jan, Partridge, Emily Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244734/
https://www.ncbi.nlm.nih.gov/pubmed/35779494
http://dx.doi.org/10.1016/j.ebiom.2022.104106