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Establishment of a Bernard-Soulier syndrome model in zebrafish

Platelets play an essential role in thrombosis and hemostasis. Abnormal hemostasis can cause spontaneous or severe post-traumatic bleeding. Bernard-Soulier syndrome (BSS) is a rare inherited bleeding disorder caused by a complete quantitative deficiency in the GPIb-IX-V complex. Multiple mutations i...

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Detalles Bibliográficos
Autores principales: Lin, Qing, Zhou, Riyang, Meng, Panpan, Wu, Liangliang, Yang, Lian, Liu, Wenyu, Wu, Jiaye, Cheng, Yuhuan, Shi, Linjuan, Zhang, Yiyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244818/
https://www.ncbi.nlm.nih.gov/pubmed/34407604
http://dx.doi.org/10.3324/haematol.2021.278893