Glutamine deprivation impairs function of infiltrating CD8(+ )T cells in hepatocellular carcinoma by inducing mitochondrial damage and apoptosis

BACKGROUND: The functions of infiltrating CD8(+ )T cells are often impaired due to tumor cells causing nutrient deprivation in the tumor microenvironment. Thus, the mechanisms of CD8(+ )T cell dysfunction have become a hot research topic, and there is increased interest on how changes in metabolomic...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Wei, Guo, Meng-Nan, Li, Ning, Pang, De-Quan, Wu, Jing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244988/
https://www.ncbi.nlm.nih.gov/pubmed/35949216
http://dx.doi.org/10.4251/wjgo.v14.i6.1124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244988/
https://www.ncbi.nlm.nih.gov/pubmed/35949216
http://dx.doi.org/10.4251/wjgo.v14.i6.1124

Ejemplares similares