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Glutamine deprivation impairs function of infiltrating CD8(+ )T cells in hepatocellular carcinoma by inducing mitochondrial damage and apoptosis
BACKGROUND: The functions of infiltrating CD8(+ )T cells are often impaired due to tumor cells causing nutrient deprivation in the tumor microenvironment. Thus, the mechanisms of CD8(+ )T cell dysfunction have become a hot research topic, and there is increased interest on how changes in metabolomic...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Baishideng Publishing Group Inc
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244988/ https://www.ncbi.nlm.nih.gov/pubmed/35949216 http://dx.doi.org/10.4251/wjgo.v14.i6.1124 |