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LIM-Homeodomain Transcription Factor LHX4 Is Required for the Differentiation of Retinal Rod Bipolar Cells and OFF-Cone Bipolar Subtypes

Retinal bipolar cells (BCs) connect with photoreceptors and relay visual information to retinal ganglion cells (RGCs). Retina-specific deletion of Lhx4 in mice results in a visual defect resembling human congenital stationary night blindness. This visual dysfunction results from the absence of rod b...

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Detalles Bibliográficos
Autores principales: Dong, Xuhui, Yang, Hua, Zhou, Xiangtian, Xie, Xiaoling, Yu, Dongliang, Guo, Luming, Xu, Mei, Zhang, Wenjun, Liang, Guoqing, Gan, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245082/
https://www.ncbi.nlm.nih.gov/pubmed/32937137
http://dx.doi.org/10.1016/j.celrep.2020.108144