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Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants

Several fast-spreading variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have become the dominant circulating strains in the COVID-19 pandemic. We report here cryo–electron microscopy structures of the full-length spike (S) trimers of the B.1.1.7 and B.1.351 variants, as well...

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Detalles Bibliográficos
Autores principales: Cai, Yongfei, Zhang, Jun, Xiao, Tianshu, Lavine, Christy L., Rawson, Shaun, Peng, Hanqin, Zhu, Haisun, Anand, Krishna, Tong, Pei, Gautam, Avneesh, Lu, Shen, Sterling, Sarah M., Walsh, Richard M., Rits-Volloch, Sophia, Lu, Jianming, Wesemann, Duane R., Yang, Wei, Seaman, Michael S., Chen, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245151/
https://www.ncbi.nlm.nih.gov/pubmed/34168070
http://dx.doi.org/10.1126/science.abi9745