Cargando…

Bookend: precise transcript reconstruction with end-guided assembly

We developed Bookend, a package for transcript assembly that incorporates data from different RNA-seq techniques, with a focus on identifying and utilizing RNA 5′ and 3′ ends. We demonstrate that correct identification of transcript start and end sites is essential for precise full-length transcript...

Descripción completa

Detalles Bibliográficos
Autores principales: Schon, Michael A., Lutzmayer, Stefan, Hofmann, Falko, Nodine, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245221/
https://www.ncbi.nlm.nih.gov/pubmed/35768836
http://dx.doi.org/10.1186/s13059-022-02700-3