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Transient post-operative overexpression of CXCR2 on monocytes of traumatic brain injury patients drives monocyte chemotaxis toward cerebrospinal fluid and enhances monocyte-mediated immunogenic cell death of neurons in vitro

BACKGROUND: After traumatic brain injury (TBI), peripheral monocytes infiltrate into the central nervous system due to disruption of the blood–brain barrier, and play an important role in neuroinflammation. However, the mechanisms regulating the movement and function of peripheral monocytes after TB...

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Detalles Bibliográficos
Autores principales: Wang, Huayang, Huang, Qibing, Zhang, Zhijie, Ji, Jian, Sun, Tao, Wang, Donghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245242/
https://www.ncbi.nlm.nih.gov/pubmed/35768823
http://dx.doi.org/10.1186/s12974-022-02535-6