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Upregulated lncARAT in Schwann cells promotes axonal regeneration by recruiting and activating proregenerative macrophages

BACKGROUND: Axonal regeneration following peripheral nerve injury (PNI) depends on the complex interaction between Schwann cells (SCs) and macrophages, but the mechanisms underlying macrophage recruitment and activation in axonal regeneration remain unclear. METHODS: RNA sequencing (RNA-seq) was con...

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Detalles Bibliográficos
Autores principales: Yin, Gang, Lin, Yaofa, Wang, Peilin, Zhou, Jun, Lin, Haodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245276/
https://www.ncbi.nlm.nih.gov/pubmed/35768768
http://dx.doi.org/10.1186/s10020-022-00501-9