Nanocrytals-Mediated Oral Drug Delivery: Enhanced Bioavailability of Amiodarone

The aim of this study was to improve the saturation solubility, dissolution profile and oral bioavailability of amiodarone hydrochloride (AMH), a highly lipophilic drug. Stabilizer (Pluronic F-127)-coated AMH nanocrystals (AMH-NCs) were developed by a combination of antisolvent precipitation and hom...

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Detalles Bibliográficos
Autores principales: Awan, Anum Munir, Farid, Arshad, Shah, Shefaat Ullah, Khan, Dildar, Ur Rehman, Fiza, Dar, Muhammad Junaid, Iftikhar, Tayyaba, Ghazanfar, Shakira, Galanakis, Charis M., Alamri, Abdulhakeem S., Asdaq, Syed Mohammed Basheeruddin, Shah, Kifayat Ullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245605/
https://www.ncbi.nlm.nih.gov/pubmed/35745871
http://dx.doi.org/10.3390/pharmaceutics14061300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245605/
https://www.ncbi.nlm.nih.gov/pubmed/35745871
http://dx.doi.org/10.3390/pharmaceutics14061300

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