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Genetic analysis of the human microglia transcriptome across brain regions, aging and disease pathologies

Microglia have emerged as important players in brain aging and pathology. To understand how genetic risk for neurological and psychiatric disorders is related to microglial function, large transcriptome studies are essential. Here, we describe the transcriptome analysis of 255 primary human microgli...

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Detalles Bibliográficos
Autores principales: de Paiva Lopes, Katia, Snijders, Gijsje J. L., Humphrey, Jack, Allan, Amanda, Sneeboer, Marjolein, Navarro, Elisa, Schilder, Brian M., Vialle, Ricardo A., Parks, Madison, Missall, Roy, van Zuiden, Welmoed, Gigase, Frederieke, Kübler, Raphael, van Berlekom, Amber Berdenis, Hicks, Emily M., Bӧttcher, Chotima, Priller, Josef, Kahn, René S., de Witte, Lot D., Raj, Towfique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245609/
https://www.ncbi.nlm.nih.gov/pubmed/34992268
http://dx.doi.org/10.1038/s41588-021-00976-y