Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria

All kingdoms of life produce essential nicotinamide dinucleotide NADP(H) using NAD kinases (NADKs). A panel of published NADK structures from bacteria, eukaryotic cytosol, and yeast mitochondria revealed similar tetrameric enzymes. Here, we present the 2.8-Å structure of the human mitochondrial kina...

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Detalles Bibliográficos
Autores principales: Du, Jin, Estrella, Michael, Solorio-Kirpichyan, Kristina, Jeffrey, Philip D., Korennykh, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245612/
https://www.ncbi.nlm.nih.gov/pubmed/35733246
http://dx.doi.org/10.1073/pnas.2200923119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245612/
https://www.ncbi.nlm.nih.gov/pubmed/35733246
http://dx.doi.org/10.1073/pnas.2200923119

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