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Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria

All kingdoms of life produce essential nicotinamide dinucleotide NADP(H) using NAD kinases (NADKs). A panel of published NADK structures from bacteria, eukaryotic cytosol, and yeast mitochondria revealed similar tetrameric enzymes. Here, we present the 2.8-Å structure of the human mitochondrial kina...

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Detalles Bibliográficos
Autores principales:	Du, Jin, Estrella, Michael, Solorio-Kirpichyan, Kristina, Jeffrey, Philip D., Korennykh, Alexei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245612/ https://www.ncbi.nlm.nih.gov/pubmed/35733246 http://dx.doi.org/10.1073/pnas.2200923119

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