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Multi-eGO: An in silico lens to look into protein aggregation kinetics at atomic resolution

Protein aggregation into amyloid fibrils is the archetype of aberrant biomolecular self-assembly processes, with more than 50 associated diseases that are mostly uncurable. Understanding aggregation mechanisms is thus of fundamental importance and goes in parallel with the structural characterizatio...

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Detalles Bibliográficos
Autores principales: Scalone, Emanuele, Broggini, Luca, Visentin, Cristina, Erba, Davide, Bačić Toplek, Fran, Peqini, Kaliroi, Pellegrino, Sara, Ricagno, Stefano, Paissoni, Cristina, Camilloni, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245614/
https://www.ncbi.nlm.nih.gov/pubmed/35737839
http://dx.doi.org/10.1073/pnas.2203181119