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Multi-eGO: An in silico lens to look into protein aggregation kinetics at atomic resolution
Protein aggregation into amyloid fibrils is the archetype of aberrant biomolecular self-assembly processes, with more than 50 associated diseases that are mostly uncurable. Understanding aggregation mechanisms is thus of fundamental importance and goes in parallel with the structural characterizatio...
Autores principales: | Scalone, Emanuele, Broggini, Luca, Visentin, Cristina, Erba, Davide, Bačić Toplek, Fran, Peqini, Kaliroi, Pellegrino, Sara, Ricagno, Stefano, Paissoni, Cristina, Camilloni, Carlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245614/ https://www.ncbi.nlm.nih.gov/pubmed/35737839 http://dx.doi.org/10.1073/pnas.2203181119 |
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