Mitochondrial calcium uniporter promotes phagocytosis-dependent activation of the NLRP3 inflammasome

Mitochondria, a highly metabolically active organelle, have been shown to play an essential role in regulating innate immune function. Mitochondrial Ca(2+) uptake via the mitochondrial Ca(2+) uniporter (MCU) is an essential process regulating mitochondrial metabolism by targeting key enzymes involve...

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Detalles Bibliográficos
Autores principales: Dong, Hong, Zhao, Bao, Chen, Jianwen, Liu, Zihao, Li, Xinghui, Li, Lupeng, Wen, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245629/
https://www.ncbi.nlm.nih.gov/pubmed/35733245
http://dx.doi.org/10.1073/pnas.2123247119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245629/
https://www.ncbi.nlm.nih.gov/pubmed/35733245
http://dx.doi.org/10.1073/pnas.2123247119

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