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A ferroptosis defense mechanism mediated by glycerol-3-phosphate dehydrogenase 2 in mitochondria

Mechanisms of defense against ferroptosis (an iron-dependent form of cell death induced by lipid peroxidation) in cellular organelles remain poorly understood, hindering our ability to target ferroptosis in disease treatment. In this study, metabolomic analyses revealed that treatment of cancer cell...

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Detalles Bibliográficos
Autores principales: Wu, Shiqi, Mao, Chao, Kondiparthi, Lavanya, Poyurovsky, Masha V., Olszewski, Kellen, Gan, Boyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245637/
https://www.ncbi.nlm.nih.gov/pubmed/35749365
http://dx.doi.org/10.1073/pnas.2121987119