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A ferroptosis defense mechanism mediated by glycerol-3-phosphate dehydrogenase 2 in mitochondria
Mechanisms of defense against ferroptosis (an iron-dependent form of cell death induced by lipid peroxidation) in cellular organelles remain poorly understood, hindering our ability to target ferroptosis in disease treatment. In this study, metabolomic analyses revealed that treatment of cancer cell...
Autores principales: | Wu, Shiqi, Mao, Chao, Kondiparthi, Lavanya, Poyurovsky, Masha V., Olszewski, Kellen, Gan, Boyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245637/ https://www.ncbi.nlm.nih.gov/pubmed/35749365 http://dx.doi.org/10.1073/pnas.2121987119 |
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