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Interpretable modeling of genotype–phenotype landscapes with state-of-the-art predictive power

Large-scale measurements linking genetic background to biological function have driven a need for models that can incorporate these data for reliable predictions and insight into the underlying biophysical system. Recent modeling efforts, however, prioritize predictive accuracy at the expense of mod...

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Detalles Bibliográficos
Autores principales: Tonner, Peter D., Pressman, Abe, Ross, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245639/
https://www.ncbi.nlm.nih.gov/pubmed/35733251
http://dx.doi.org/10.1073/pnas.2114021119