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Immune checkpoint inhibitors unleash pathogenic immune responses against the microbiota

Immune checkpoint inhibitors (ICIs) are essential components of the cancer therapeutic armamentarium. While ICIs have demonstrated remarkable clinical responses, they can be accompanied by immune-related adverse events (irAEs). These inflammatory side effects are of unclear etiology and impact virtu...

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Detalles Bibliográficos
Autores principales: Hu, Zishuo Ian, Link, Verena M., Lima-Junior, Djalma S., Delaleu, Jérémie, Bouladoux, Nicolas, Han, Seong-Ji, Collins, Nicholas, Belkaid, Yasmine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245641/
https://www.ncbi.nlm.nih.gov/pubmed/35727974
http://dx.doi.org/10.1073/pnas.2200348119