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Mapping functional regions of essential bacterial proteins with dominant-negative protein fragments
Massively parallel measurements of dominant-negative inhibition by protein fragments have been used to map protein interaction sites and discover peptide inhibitors. However, the underlying principles governing fragment-based inhibition have thus far remained unclear. Here, we adapted a high-through...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245647/ https://www.ncbi.nlm.nih.gov/pubmed/35749361 http://dx.doi.org/10.1073/pnas.2200124119 |