Aging can transform single-component protein condensates into multiphase architectures

Phase-separated biomolecular condensates that contain multiple coexisting phases are widespread in vitro and in cells. Multiphase condensates emerge readily within multicomponent mixtures of biomolecules (e.g., proteins and nucleic acids) when the different components present sufficient physicochemi...

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Detalles Bibliográficos
Autores principales: Garaizar, Adiran, Espinosa, Jorge R., Joseph, Jerelle A., Krainer, Georg, Shen, Yi, Knowles, Tuomas P.J., Collepardo-Guevara, Rosana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245653/
https://www.ncbi.nlm.nih.gov/pubmed/35727989
http://dx.doi.org/10.1073/pnas.2119800119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245653/
https://www.ncbi.nlm.nih.gov/pubmed/35727989
http://dx.doi.org/10.1073/pnas.2119800119

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