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Metal cofactor stabilization by a partner protein is a widespread strategy employed for amidase activation

Construction and remodeling of the bacterial peptidoglycan (PG) cell wall must be carefully coordinated with cell growth and division. Central to cell wall construction are hydrolases that cleave bonds in peptidoglycan. These enzymes also represent potential new antibiotic targets. One such hydrolas...

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Detalles Bibliográficos
Autores principales: Page, Julia E., Skiba, Meredith A., Do, Truc, Kruse, Andrew C., Walker, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245657/
https://www.ncbi.nlm.nih.gov/pubmed/35733252
http://dx.doi.org/10.1073/pnas.2201141119