A small molecule redistributes iron in ferroportin-deficient mice and patient-derived primary macrophages

Deficiencies of the transmembrane iron-transporting protein ferroportin (FPN1) cause the iron misdistribution that underlies ferroportin disease, anemia of inflammation, and several other human diseases and conditions. A small molecule natural product, hinokitiol, was recently shown to serve as a su...

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Detalles Bibliográficos
Autores principales: Ekaputri, Stella, Choi, Eun-Kyung, Sabelli, Manuela, Aring, Luisa, Green, Kelsie J., Chang, JuOae, Bao, Kai, Choi, Hak Soo, Iwase, Shigeki, Kim, Jonghan, Corradini, Elena, Pietrangelo, Antonello, Burke, Martin D., Seo, Young Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245668/
https://www.ncbi.nlm.nih.gov/pubmed/35737834
http://dx.doi.org/10.1073/pnas.2121400119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245668/
https://www.ncbi.nlm.nih.gov/pubmed/35737834
http://dx.doi.org/10.1073/pnas.2121400119

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