Tas2R activation relaxes airway smooth muscle by release of Gα(t) targeting on AChR signaling

Both chronic obstructive pulmonary disease (COPD) and asthma are severe respiratory diseases. Bitter receptor–mediated bronchodilation is a potential therapy for asthma, but the mechanism underlying the agonistic relaxation of airway smooth muscle (ASM) is not well defined. By exploring the ASM rela...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Yu-Wei, Sun, Jie, Wang, Ye, Chen, Cai-Ping, Tao, Tao, Ma, Ming, Chen, Xin, Zhang, Xue-Na, Yang, Li-Yuan, Zhang, Zhong-Liang, Li, Ye-Qiong, Jiang, Zhi-Hui, Qiu, Tian-Tian, Wang, Han, Pan, Yang, Zhang, Jian, Chen, Hua-Qun, Wang, Pei, Zhu, Min-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245679/
https://www.ncbi.nlm.nih.gov/pubmed/35737832
http://dx.doi.org/10.1073/pnas.2121513119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245679/
https://www.ncbi.nlm.nih.gov/pubmed/35737832
http://dx.doi.org/10.1073/pnas.2121513119

Ejemplares similares