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Interaction between S4 and the phosphatase domain mediates electrochemical coupling in voltage-sensing phosphatase (VSP)

Voltage-sensing phosphatase (VSP) consists of a voltage sensor domain (VSD) and a cytoplasmic catalytic region (CCR), which is similar to phosphatase and tensin homolog (PTEN). How the VSD regulates the innate enzyme component of VSP remains unclear. Here, we took a combined approach that entailed t...

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Detalles Bibliográficos
Autores principales: Mizutani, Natsuki, Kawanabe, Akira, Jinno, Yuka, Narita, Hirotaka, Yonezawa, Tomoko, Nakagawa, Atsushi, Okamura, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245683/
https://www.ncbi.nlm.nih.gov/pubmed/35733115
http://dx.doi.org/10.1073/pnas.2200364119