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Loss of adipose TET proteins enhances β-adrenergic responses and protects against obesity by epigenetic regulation of β3-AR expression

β-adrenergic receptor (β-AR) signaling plays predominant roles in modulating energy expenditure by triggering lipolysis and thermogenesis in adipose tissue, thereby conferring obesity resistance. Obesity is associated with diminished β3-adrenergic receptor (β3-AR) expression and decreased β-adrenerg...

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Detalles Bibliográficos
Autores principales: Byun, Seongjun, Lee, Chan Hyeong, Jeong, Hyeongmin, Kim, Hyejin, Kwon, Hyug Moo, Park, Sungho, Myung, Kyungjae, An, Jungeun, Ko, Myunggon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245707/
https://www.ncbi.nlm.nih.gov/pubmed/35737830
http://dx.doi.org/10.1073/pnas.2205626119