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Dose Proportionality and Steady-State Pharmacokinetics of Serdexmethylphenidate/Dexmethylphenidate, a Novel Prodrug Combination to Treat Attention-Deficit/Hyperactivity Disorder

OBJECTIVE: The study was designed to determine (1) the pharmacokinetic (PK) profile of dexmethylphenidate (d-MPH) after oral administration of three dosage strengths of a new treatment containing d-MPH and a novel prodrug, serdexmethylphenidate (SDX); (2) the dose proportionality of the different SD...

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Detalles Bibliográficos
Autores principales: Braeckman, Rene, Guenther, Sven, Mickle, Travis C., Barrett, Andrew C., Smith, Adam, Oh, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245728/
https://www.ncbi.nlm.nih.gov/pubmed/35666231
http://dx.doi.org/10.1089/cap.2022.0015