Structure-activity relationship studies for inhibitors for vancomycin-resistant Enterococcus and human carbonic anhydrases

Vancomycin-resistant enterococci (VRE), consisting of pathogenic Enterococcus faecalis and E. faecium, is a leading cause of hospital-acquired infections (HAIs). We recently repurposed the FDA-approved human carbonic anhydrase (CA) inhibitor acetazolamide (AZM) against VRE agent with the likely mech...

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Detalles Bibliográficos
Autores principales: An, Weiwei, Holly, Katrina J., Nocentini, Alessio, Imhoff, Ryan D., Hewitt, Chad. S., Abutaleb, Nader S., Cao, Xufeng, Seleem, Mohamed N., Supuran, Claudiu T., Flaherty, Daniel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246096/
https://www.ncbi.nlm.nih.gov/pubmed/35758212
http://dx.doi.org/10.1080/14756366.2022.2092729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246096/
https://www.ncbi.nlm.nih.gov/pubmed/35758212
http://dx.doi.org/10.1080/14756366.2022.2092729

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