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Solid lipid nanoparticles to improve bioaccessibility and permeability of orally administered maslinic acid

Maslinic acid (MA) is a plant-derived, low water-soluble compound with antitumor activity. We have formulated MA in the form of solid lipid nanoparticles (SLNs) with three different shell compositions: Poloxamer 407 (PMA), dicarboxylic acid-Poloxamer 407 (PCMA), and HA-coated PCMA (PCMA-HA). These S...

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Detalles Bibliográficos
Autores principales: Aguilera-Garrido, Aixa, Arranz, Elena, Gálvez-Ruiz, María José, Marchal, Juan Antonio, Galisteo-González, Francisco, Giblin, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246121/
https://www.ncbi.nlm.nih.gov/pubmed/35762633
http://dx.doi.org/10.1080/10717544.2022.2086937