Benzenesulfonamides with different rigidity-conferring linkers as carbonic anhydrase inhibitors: an insight into the antiproliferative effect on glioblastoma, pancreatic, and breast cancer cells

Among the chemotypes studied for selective inhibition of tumour-associated carbonic anhydrases (CAs), SLC-0111, a ureido-bearing benzenesulfonamide CA IX inhibitor, displayed promising antiproliferative effects in cancer cells in vitro and in vivo, being in Phase Ib/II clinical development. To explo...

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Detalles Bibliográficos
Autores principales: Liguori, Francesco, Carradori, Simone, Ronca, Roberto, Rezzola, Sara, Filiberti, Serena, Carta, Fabrizio, Turati, Marta, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246135/
https://www.ncbi.nlm.nih.gov/pubmed/35768159
http://dx.doi.org/10.1080/14756366.2022.2091557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246135/
https://www.ncbi.nlm.nih.gov/pubmed/35768159
http://dx.doi.org/10.1080/14756366.2022.2091557

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