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Intragenomic variation in non-adaptive nucleotide biases causes underestimation of selection on synonymous codon usage
Patterns of non-uniform usage of synonymous codons vary across genes in an organism and between species across all domains of life. This codon usage bias (CUB) is due to a combination of non-adaptive (e.g. mutation biases) and adaptive (e.g. natural selection for translation efficiency/accuracy) evo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246145/ https://www.ncbi.nlm.nih.gov/pubmed/35714134 http://dx.doi.org/10.1371/journal.pgen.1010256 |