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The HDAC9-associated risk locus promotes coronary artery disease by governing TWIST1

Genome wide association studies (GWAS) have identified thousands of single nucleotide polymorphisms (SNPs) associated with the risk of common disorders. However, since the large majority of these risk SNPs reside outside gene-coding regions, GWAS generally provide no information about causal mechani...

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Detalles Bibliográficos
Autores principales: Ma, Lijiang, Bryce, Nicole S., Turner, Adam W., Di Narzo, Antonio F., Rahman, Karishma, Xu, Yang, Ermel, Raili, Sukhavasi, Katyayani, d’Escamard, Valentina, Chandel, Nirupama, V’Gangula, Bhargavi, Wolhuter, Kathryn, Kadian-Dodov, Daniella, Franzen, Oscar, Ruusalepp, Arno, Hao, Ke, Miller, Clint L., Björkegren, Johan L. M., Kovacic, Jason C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246173/
https://www.ncbi.nlm.nih.gov/pubmed/35714152
http://dx.doi.org/10.1371/journal.pgen.1010261