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PACSIN1 is indispensable for amphisome-lysosome fusion during basal autophagy and subsets of selective autophagy
Autophagy is an indispensable process that degrades cytoplasmic materials to maintain cellular homeostasis. During autophagy, double-membrane autophagosomes surround cytoplasmic materials and either fuse with endosomes (called amphisomes) and then lysosomes, or directly fuse with lysosomes, in both...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246181/ https://www.ncbi.nlm.nih.gov/pubmed/35771772 http://dx.doi.org/10.1371/journal.pgen.1010264 |