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Clusters of apoptotic signaling molecule-enriched rafts, CASMERs: membrane platforms for protein assembly in Fas/CD95 signaling and targets in cancer therapy

Mammalian cells show the ability to commit suicide through the activation of death receptors at the cell surface. Death receptors, among which Fas/CD95 is one of their most representative members, lack enzymatic activity, and depend on protein–protein interactions to signal apoptosis. Fas/CD95 death...

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Detalles Bibliográficos
Autores principales: Mollinedo, Faustino, Gajate, Consuelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246327/
https://www.ncbi.nlm.nih.gov/pubmed/35587168
http://dx.doi.org/10.1042/BST20211115