CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact

The ∼30 Mb genomes of the Plasmodium parasites that cause malaria each encode ∼5000 genes, but the functions of the majority remain unknown. This is due to a paucity of functional annotation from sequence homology, which is compounded by low genetic tractability compared with many model organisms. I...

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Detalles Bibliográficos
Autores principales: Ishizaki, Takahiro, Hernandez, Sophia, Paoletta, Martina S., Sanderson, Theo, Bushell, Ellen S.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246331/
https://www.ncbi.nlm.nih.gov/pubmed/35621119
http://dx.doi.org/10.1042/BST20210281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246331/
https://www.ncbi.nlm.nih.gov/pubmed/35621119
http://dx.doi.org/10.1042/BST20210281

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