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A nerve injury–specific long noncoding RNA promotes neuropathic pain by increasing Ccl2 expression

Maladaptive changes of nerve injury–associated genes in dorsal root ganglia (DRGs) are critical for neuropathic pain genesis. Emerging evidence supports the role of long noncoding RNAs (lncRNAs) in regulating gene transcription. Here we identified a conserved lncRNA, named nerve injury–specific lncR...

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Detalles Bibliográficos
Autores principales: Du, Shibin, Wu, Shaogen, Feng, Xiaozhou, Wang, Bing, Xia, Shangzhou, Liang, Lingli, Zhang, Li, Govindarajalu, Gokulapriya, Bunk, Alexander, Kadakia, Feni, Mao, Qingxiang, Guo, Xinying, Zhao, Hui, Berkman, Tolga, Liu, Tong, Li, Hong, Stillman, Jordan, Bekker, Alex, Davidson, Steve, Tao, Yuan-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246381/
https://www.ncbi.nlm.nih.gov/pubmed/35775484
http://dx.doi.org/10.1172/JCI153563