Glycoengineered anti-CD39 promotes anticancer responses by depleting suppressive cells and inhibiting angiogenesis in tumor models

Immunosuppressive cells accumulating in the tumor microenvironment constitute a formidable barrier that interferes with current immunotherapeutic approaches. A unifying feature of these tumor-associated immune and vascular endothelial cells appears to be the elevated expression of ectonucleotidase C...

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Detalles Bibliográficos
Autores principales: Zhang, Haohai, Feng, Lili, de Andrade Mello, Paola, Mao, Changchuin, Near, Richard, Csizmadia, Eva, Chan, Leo Li-Ying, Enjyoji, Keiichi, Gao, Wenda, Zhao, Haitao, Robson, Simon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246388/
https://www.ncbi.nlm.nih.gov/pubmed/35775486
http://dx.doi.org/10.1172/JCI157431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246388/
https://www.ncbi.nlm.nih.gov/pubmed/35775486
http://dx.doi.org/10.1172/JCI157431

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