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Clinical Evaluation of Antiphospholipase A2 Receptor IgG4 level and Its IgG4-to-IgG Ratio Based on Quantitative Immunoassays in Idiopathic Membranous Nephropathy

BACKGROUND: Phospholipase A2 receptor (PLA2R), located at the membrane of glomerular podocyte, is the major autoantigen of idiopathic membranous nephropathy (IMN), and its antibodies with a predominant IgG4 subclass lead to pathological lesions. Further studies could be performed to validate the cli...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Huang, Yiqing, Huang, Biao, Chen, Xiaolei, Zhou, Bin, Zou, Pei, Wang, Liang, Liu, Xiaobin, Sheng, Huiming, Xie, Minhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246623/
https://www.ncbi.nlm.nih.gov/pubmed/35782060
http://dx.doi.org/10.1155/2022/9127520