Development of a sandwich enzyme-linked immunosorbent assay (ELISA) to quantify γ-glutamyl-carboxylated clotting factor IX and assess redox susceptibility of anticoagulant chemicals

Anticoagulant chemicals (ACCs) such as warfarin are widely used in medical applications as well as for their rodenticide properties. Their efficacy is greatly influenced by polymorphisms in the gene encoding vitamin K epoxide reductase (VKOR). Evaluation of the activity of ACCs toward VKOR variants...

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Detalles Bibliográficos
Autores principales: SATO, Ryo, WATANABE, Kanami, KAMATA, Ryo, TAKEDA, Kazuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2022
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246686/
https://www.ncbi.nlm.nih.gov/pubmed/35444089
http://dx.doi.org/10.1292/jvms.22-0079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246686/
https://www.ncbi.nlm.nih.gov/pubmed/35444089
http://dx.doi.org/10.1292/jvms.22-0079

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