High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3

INTRODUCTION: The organic cation transporter 3 (OCT3, SLC22A3) is ubiquitously expressed and interacts with a wide array of compounds including endogenous molecules, environmental toxins and prescription drugs. Understudied as a determinant of pharmacokinetics and pharmacodynamics, OCT3 has the pote...

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Detalles Bibliográficos
Autores principales: Chen, Eugene C., Matsson, Pär, Azimi, Mina, Zhou, Xujia, Handin, Niklas, Yee, Sook Wah, Artursson, Per, Giacomini, Kathleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246766/
https://www.ncbi.nlm.nih.gov/pubmed/35089508
http://dx.doi.org/10.1007/s11095-022-03171-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246766/
https://www.ncbi.nlm.nih.gov/pubmed/35089508
http://dx.doi.org/10.1007/s11095-022-03171-8

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