Breast cancer patient-derived organoid screening implicates the repressor NCOR2 in cytotoxic stress response and anti-tumor immunity

Resistance to anti-tumor treatment contributes to patient mortality. Functional proteomic screening of chemotherapy-treated breast cancer patient-derived organoids (PDOs) identified nuclear co-repressor-2 (NCOR2) histone deacetylase as an inhibitor of cytotoxic stress response and anti-tumor immunit...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsai, Kelvin K., Huang, Shenq-Shyang, Northey, Jason J., Liao, Wen-Ying, Hsu, Chung-Chi, Cheng, Li-Hsin, Werner, Michael E., Chuu, Chih-Pin, Chatterjee, Chandrima, Lakins, Jonathan N., Weaver, Valerie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246917/
https://www.ncbi.nlm.nih.gov/pubmed/35618935
http://dx.doi.org/10.1038/s43018-022-00375-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246917/
https://www.ncbi.nlm.nih.gov/pubmed/35618935
http://dx.doi.org/10.1038/s43018-022-00375-0

Ejemplares similares