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Ligand-induced structural transitions combined with paramagnetic ions facilitate unambiguous NMR assignments of methyl groups in large proteins

NMR spectroscopy allows the study of biomolecules in close-to-native conditions. Structural information can be inferred from the NMR spectra when an assignment is available. Protein assignment is usually a time-consuming task, being specially challenging in the case of large, supramolecular systems....

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Detalles Bibliográficos
Autores principales: Mühlberg, Lars, Alarcin, Tuncay, Maass, Thorben, Creutznacher, Robert, Küchler, Richard, Mallagaray, Alvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247001/
https://www.ncbi.nlm.nih.gov/pubmed/35397749
http://dx.doi.org/10.1007/s10858-022-00394-0