cGAS-STING signaling encourages immune cell overcoming of fibroblast barricades in pancreatic cancer

Immune checkpoint blockade (ICB) treatment improves the prognosis of several types of solid tumors, however, responsiveness to ICB therapy remains low in pancreatic ductal adenocarcinoma (PDACs), which has a rich tumor microenvironment (TME). The TME is composed of various stromal cells, including c...

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Detalles Bibliográficos
Autores principales: Kabashima, Ayano, Matsuo, Yuki, Ito, Saki, Akiyama, Yoshimitsu, Ishii, Takeshi, Shimada, Shu, Masamune, Atsushi, Tanabe, Minoru, Tanaka, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247053/
https://www.ncbi.nlm.nih.gov/pubmed/35773436
http://dx.doi.org/10.1038/s41598-022-14297-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247053/
https://www.ncbi.nlm.nih.gov/pubmed/35773436
http://dx.doi.org/10.1038/s41598-022-14297-5

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