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cGAS-STING signaling encourages immune cell overcoming of fibroblast barricades in pancreatic cancer
Immune checkpoint blockade (ICB) treatment improves the prognosis of several types of solid tumors, however, responsiveness to ICB therapy remains low in pancreatic ductal adenocarcinoma (PDACs), which has a rich tumor microenvironment (TME). The TME is composed of various stromal cells, including c...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247053/ https://www.ncbi.nlm.nih.gov/pubmed/35773436 http://dx.doi.org/10.1038/s41598-022-14297-5 |