Semi-automated approach for generation of biological networks on drug-induced cholestasis, steatosis, hepatitis, and cirrhosis

Drug-induced liver injury (DILI) is one of the leading reasons for discontinuation of a new drug development project. Diverse machine learning or deep learning models have been developed to predict DILI. However, these models have not provided an adequate understanding of the mechanisms leading to D...

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Detalles Bibliográficos
Autores principales: Shin, Hyun Kil, Florean, Oana, Hardy, Barry, Doktorova, Tatyana, Kang, Myung-Gyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247124/
https://www.ncbi.nlm.nih.gov/pubmed/35865277
http://dx.doi.org/10.1007/s43188-022-00124-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247124/
https://www.ncbi.nlm.nih.gov/pubmed/35865277
http://dx.doi.org/10.1007/s43188-022-00124-6

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