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Semi-automated approach for generation of biological networks on drug-induced cholestasis, steatosis, hepatitis, and cirrhosis
Drug-induced liver injury (DILI) is one of the leading reasons for discontinuation of a new drug development project. Diverse machine learning or deep learning models have been developed to predict DILI. However, these models have not provided an adequate understanding of the mechanisms leading to D...
Autores principales: | Shin, Hyun Kil, Florean, Oana, Hardy, Barry, Doktorova, Tatyana, Kang, Myung-Gyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247124/ https://www.ncbi.nlm.nih.gov/pubmed/35865277 http://dx.doi.org/10.1007/s43188-022-00124-6 |
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