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Changes in the Transcriptome and Chromatin Landscape in BRAFi-Resistant Melanoma Cells

Metastatic and drug-resistant melanoma are leading causes of skin cancer–associated death. Mitogen-associated protein kinase (MAPK) pathway inhibitors and immunotherapies have provided substantial benefits to patients with melanoma. However, long-term therapeutic efficacy has been limited due to eme...

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Detalles Bibliográficos
Autores principales: Reddi, Kiran Kumar, Guruvaiah, Praveen, Edwards, Yvonne J. K., Gupta, Romi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247198/
https://www.ncbi.nlm.nih.gov/pubmed/35785205
http://dx.doi.org/10.3389/fonc.2022.937831