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Comparison of viral propagation and drug response among SARS-CoV-2 VOCs using replicons capable of recapitulating virion assembly and release

Several variants of concern (VOCs) have emerged since the WIV04 strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first isolated in January 2020. Due to mutations in the spike (S) protein, these VOCs have evolved to enhance viral infectivity and immune evasion. However, whet...

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Detalles Bibliográficos
Autores principales: Tian, Lingqian, Liu, Qiuhong, Pei, Rongjuan, Chen, Yingshan, Xu, Chonghui, Tang, Jielin, Sun, Hao, Liu, Kunpeng, Yang, Qi, Yang, Lei, Li, Leshan, Zhang, Yongli, Zhou, Yuan, Shan, Chao, Hu, Xue, Chen, Xinwen, Wang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247232/
https://www.ncbi.nlm.nih.gov/pubmed/35781091
http://dx.doi.org/10.1016/j.virs.2022.06.008