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Nicotinamide Promotes Formation of Retinal Organoids From Human Pluripotent Stem Cells via Enhanced Neural Cell Fate Commitment

Retinal organoids (ROs) derived from human pluripotent stem cells (hPSCs) recapitulate key features of retinogenesis and provide a promising platform to study retinal development and disease in a human context. Although multiple protocols are currently in use, hPSCs exhibit tremendous variability in...

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Detalles Bibliográficos
Autores principales: Regent, Florian, Batz, Zachary, Kelley, Ryan A., Gieser, Linn, Swaroop, Anand, Chen, Holly Y., Li, Tiansen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9247291/
https://www.ncbi.nlm.nih.gov/pubmed/35783089
http://dx.doi.org/10.3389/fncel.2022.878351